Frontiers in Pharmacology Sengupta A, Dorn A, Jamshidi M, Schwob M, Hassan W, De Maddalena LL, Hugi A, Stucki AO, Dorn P, Marti TM, Wisser O, Stucki JD, Krebs T, Hobi N and Guenat OT Abstract Prolonged exposure to environmental respirable toxicants can lead to the development and worsening of severe respiratory diseases such as...

Frontiers in Toxicology Sengupta, A., Roldan, N., Kiener, M., Froment, L., Raggi, G., Imler, T., de Maddalena, L., Rapet, A., May, T., Carius, P., Lehr, C., Geiser, T., Marti, T. M., Stucki, J. D., Hobi, N., & Guenat, O. T. Abstract The evaluation of inhalation toxicity, drug safety and efficacy assessment, as well as the...

Frontiers in Medicine Mirjam Kiener, Nuria Roldan, Carlos Machahua, Arunima Sengupta, Thomas Geiser, Olivier Thierry Guenat, Manuela Funke-Chambour, Nina Hobi and Marianna Kruithof-de Julio Abstract The coronavirus disease 2019 (COVID-19) pandemic has caused considerable socio-economic burden, which fueled the development of treatment strategies and vaccines at an unprecedented speed. However, our knowledge on disease recovery...

European Respiratory Journal Clementine Richter, Alberto Hidalgo, Patrick Carius, Nuria Roldan, Janick Stucki, Nina Hobi, Nicole Schneider-Daum, Calus-Michael Lehr Abstract The pharmaceutical industry is in rising need for alternative methods that minimise animal testing during early drug development, mainly because of the poor transferability from animal to human, costs or ethical issues. However, traditional cellular models fail to reproduce essential physio-pathological, systemic and structural aspects. In this sense, organ-on-chips have...